This paper proposes a reinforcement learning (RL)-aided cognitive framework for massive MIMO-based integrated sensing and communication (ISAC) systems employing a uniform planar array (UPA). The focus is on enhancing radar sensing performance in environments with unknown and dynamic disturbance characteristics. A Wald-type detector is employed for robust target detection under non-Gaussian clutter, while a SARSA-based RL algorithm enables adaptive estimation of target positions without prior environmental knowledge. Based on the RL-derived sensing information, a joint waveform optimization strategy is formulated to balance radar sensing accuracy and downlink communication throughput. The resulting design provides an adaptive trade-off between detection performance and achievable sum rate through an analytically derived closed-form solution. Monte Carlo simulations demonstrate that the proposed cognitive ISAC framework achieves significantly improved detection probability compared to orthogonal and non-learning adaptive baselines, while maintaining competitive communication performance. These results underline the potential of RL-assisted sensing for robust and spectrum-efficient ISAC in next-generation wireless networks.

Sample size calculations for power analysis are critical for clinical research and trial design, yet their complexity and reliance on statistical expertise create barriers for many researchers. We introduce PowerGPT, an AI-powered system integrating large language models (LLMs) with statistical engines to automate test selection and sample size estimation in trial design. In a randomized trial to evaluate its effectiveness, PowerGPT significantly improved task completion rates (99.3% vs. 88.9% for test selection, 99.3% vs. 77.8% for sample size calculation) and accuracy (94.1% vs. 55.4% in sample size estimation, p < 0.001), while reducing average completion time (4.0 vs. 9.3 minutes, p < 0.001). These gains were consistent across various statistical tests and benefited both statisticians and non-statisticians as well as bridging expertise gaps. Already under deployment across multiple institutions, PowerGPT represents a scalable AI-driven approach that enhances accessibility, efficiency, and accuracy in statistical power analysis for clinical research.

Evolutionary approaches have previously been shown to be effective learning methods for a diverse set of domains. However, the domain of game-playing poses a particular challenge for evolutionary methods due to the inherently large state space of video games. As the size of the input state expands, the size of the policy must also increase in order to effectively learn the temporal patterns in the game space. Consequently, a larger policy must contain more trainable parameters, exponentially increasing the size of the search space. Any increase in search space is highly problematic for evolutionary methods, as increasing the number of trainable parameters is inversely correlated with convergence speed. To reduce the size of the input space while maintaining a meaningful representation of the original space, we introduce Sparse Cosine Optimized Policy Evolution (SCOPE). SCOPE utilizes the Discrete Cosine Transform (DCT) as a pseudo attention mechanism, transforming an input state into a coefficient matrix. By truncating and applying sparsification to this matrix, we reduce the dimensionality of the input space while retaining the highest energy features of the original input. We demonstrate the effectiveness of SCOPE as the policy for the Atari game Space Invaders. In this task, SCOPE with CMA-ES outperforms evolutionary methods that consider an unmodified input state, such as OpenAI-ES and HyperNEAT. SCOPE also outperforms simple reinforcement learning methods, such as DQN and A3C. SCOPE achieves this result through reducing the input size by 53% from 33,600 to 15,625 then using a bilinear affine mapping of sparse DCT coefficients to policy actions learned by the CMA-ES algorithm.

Evolutionary methods have previously been shown to be an effective learning method for walking gaits on hexapod robots. However, the ability of these algorithms to evolve an effective policy rapidly degrades as the input space becomes more complex. This degradation is due to the exponential growth of the solution space, resulting from an increasing parameter count to handle a more complex input. In order to address this challenge, we introduce Sparse Cosine Optimized Policy Evolution (SCOPE). SCOPE utilizes the Discrete Cosine Transform (DCT) to learn directly from the feature coefficients of an input matrix. By truncating the coefficient matrix returned by the DCT, we can reduce the dimensionality of an input while retaining the highest energy features of the original input. We demonstrate the effectiveness of this method by using SCOPE to learn the gait of a hexapod robot. The hexapod controller is given a matrix input containing time-series information of previous poses, which are then transformed to gait parameters by an evolved policy. In this task, the addition of SCOPE to a reference algorithm achieves a 20% increase in efficacy. SCOPE achieves this result by reducing the total input size of the time-series pose data from 2700 to 54, a 98% decrease. Additionally, SCOPE is capable of compressing an input to any output shape, provided that each output dimension is no greater than the corresponding input dimension. This paper demonstrates that SCOPE is capable of significantly compressing the size of an input to an evolved controller, resulting in a statistically significant gain in efficacy.

The rising rate of drug-related deaths in the United States, largely driven by fentanyl, requires timely and accurate surveillance. However, critical overdose data are often buried in free-text coroner reports, leading to delays and information loss when coded into ICD (International Classification of Disease)-10 classifications. Natural language processing (NLP) models may automate and enhance overdose surveillance, but prior applications have been limited. A dataset of 35,433 death records from multiple U.S. jurisdictions in 2020 was used for model training and internal testing. External validation was conducted using a novel separate dataset of 3,335 records from 2023-2024. Multiple NLP approaches were evaluated for classifying specific drug involvement from unstructured death certificate text. These included traditional single- and multi-label classifiers, as well as fine-tuned encoder-only language models such as Bidirectional Encoder Representations from Transformers (BERT) and BioClinicalBERT, and contemporary decoder-only large language models such as Qwen 3 and Llama 3. Model performance was assessed using macro-averaged F1 scores, and 95% confidence intervals were calculated to quantify uncertainty. Fine-tuned BioClinicalBERT models achieved near-perfect performance, with macro F1 scores >=0.998 on the internal test set. External validation confirmed robustness (macro F1=0.966), outperforming conventional machine learning, general-domain BERT models, and various decoder-only large language models. NLP models, particularly fine-tuned clinical variants like BioClinicalBERT, offer a highly accurate and scalable solution for overdose death classification from free-text reports. These methods can significantly accelerate surveillance workflows, overcoming the limitations of manual ICD-10 coding and supporting near real-time detection of emerging substance use trends.

--This paper investigates the application of Neuroevo-lution of Augmenting T opologies (NEA T) to automate gameplay in Dark Souls, a notoriously challenging action role-playing game characterized by complex combat mechanics, dynamic environments, and high-dimensional visual inputs. T o facilitate this approach, we introduce the Dark Souls API (DSAPI), a novel Python framework leveraging real-time computer vision techniques for extracting critical game metrics, including player and enemy health states. Using NEA T, agents evolve effective combat strategies for defeating the Asylum Demon, the game's initial boss, without predefined behaviors or domain-specific heuristics. Experimental results demonstrate that evolved agents achieve up to a 35% success rate, indicating the viability of neuroevolution in addressing complex, visually intricate gameplay scenarios. This work represents an interesting application of vision-based neuroevolution, highlighting its potential use in a wide range of challenging game environments lacking direct API support or well-defined state representations. The development of artificial intelligence (AI) capable of playing video games at a human or superhuman level has long been an important benchmark in AI research [1], [2].

StarCraft: Brood War remains a challenging benchmark for artificial intelligence research, particularly in the domain of macromanagement, where long-term strategic planning is required. Traditional approaches to StarCraft AI rely on rule-based systems or supervised deep learning, both of which face limitations in adaptability and computational efficiency. In this work, we introduce NeuroPAL, a neuroevolutionary framework that integrates Neuroevolution of Augmenting Topologies (NEAT) with Punctuated Anytime Learning (PAL) to improve the efficiency of evolutionary training. By alternating between frequent, low-fidelity training and periodic, high-fidelity evaluations, PAL enhances the sample efficiency of NEAT, enabling agents to discover effective strategies in fewer training iterations. We evaluate NeuroPAL in a fixed-map, single-race scenario in StarCraft: Brood War and compare its performance to standard NEAT-based training. Our results show that PAL significantly accelerates the learning process, allowing the agent to reach competitive levels of play in approximately half the training time required by NEAT alone. Additionally, the evolved agents exhibit emergent behaviors such as proxy barracks placement and defensive building optimization, strategies commonly used by expert human players. These findings suggest that structured evaluation mechanisms like PAL can enhance the scalability and effectiveness of neuroevolution in complex real-time strategy environments.

Many existing approaches to generalizing statistical inference amidst distribution shift operate under the covariate shift assumption, which posits that the conditional distribution of unobserved variables given observable ones is invariant across populations. However, recent empirical investigations have demonstrated that adjusting for shift in observed variables (covariate shift) is often insufficient for generalization. In other words, covariate shift does not typically ``explain away'' the distribution shift between settings. As such, addressing the unknown yet non-negligible shift in the unobserved variables given observed ones (conditional shift) is crucial for generalizable inference. In this paper, we present a series of empirical evidence from two large-scale multi-site replication studies to support a new role of covariate shift in ``predicting'' the strength of the unknown conditional shift. Analyzing 680 studies across 65 sites, we find that even though the conditional shift is non-negligible, its strength can often be bounded by that of the observable covariate shift. However, this pattern only emerges when the two sources of shifts are quantified by our proposed standardized, ``pivotal'' measures. We then interpret this phenomenon by connecting it to similar patterns that can be theoretically derived from a random distribution shift model. Finally, we demonstrate that exploiting the predictive role of covariate shift leads to reliable and efficient uncertainty quantification for target estimates in generalization tasks with partially observed data. Overall, our empirical and theoretical analyses suggest a new way to approach the problem of distributional shift, generalizability, and external validity.

Propaganda plays a critical role in shaping public opinion and fueling disinformation. While existing research primarily focuses on identifying propaganda techniques, it lacks the ability to capture the broader motives and the impacts of such content. To address these challenges, we introduce propainsight, a conceptual framework grounded in foundational social science research, which systematically dissects propaganda into techniques, arousal appeals, and underlying intent. propainsight offers a more granular understanding of how propaganda operates across different contexts. Additionally, we present propagaze, a novel dataset that combines human-annotated data with high-quality synthetic data generated through a meticulously designed pipeline. Our experiments show that off-the-shelf LLMs struggle with propaganda analysis, but training with propagaze significantly improves performance. Fine-tuned Llama-7B-Chat achieves 203.4% higher text span IoU in technique identification and 66.2% higher BertScore in appeal analysis compared to 1-shot GPT-4-Turbo. Moreover, propagaze complements limited human-annotated data in data-sparse and cross-domain scenarios, showing its potential for comprehensive and generalizable propaganda analysis.

Tables play a crucial role in conveying information in various domains. We propose a Plan-then-Reason framework to answer different types of user queries over tables with sentence context. The framework first plans the reasoning paths over the context, then assigns each step to program-based or textual reasoning to reach the final answer. This framework enhances the table reasoning abilities for both in-context learning and fine-tuning methods. GPT-3.5-Turbo following Plan-then-Reason framework surpasses other prompting baselines without self-consistency while using less API calls and in-context demonstrations. We also construct an instruction tuning set TrixInstruct to evaluate the effectiveness of fine-tuning with this framework. We present ProTrix model family by finetuning models on TrixInstruct. Our experiments show that ProTrix family generalizes to diverse unseen tabular tasks with only 6k training instances. We further demonstrate that ProTrix can generate accurate and faithful explanations to answer complex free-form questions. Our work underscores the importance of the planning and reasoning abilities towards a model over tabular tasks with generalizability and interpretability. We open-source our dataset and models at https://github.com/WilliamZR/ProTrix.